The main operations of the Hongwanji International Center include the research, translation, and publication of Buddhist texts and articles; coordination of activities involving the overseas temples; organization and administration of overseas events involving Hongwanji personnel; presentation of an annual lecture series featuring eminent scholars; training seminars for both active overseas (kaikyoshi) ministers and Japanese ministerial aspirants; and point of contact for inquiries and communications between the Hongwanji headquarters and abroad.

The Center also provides student housing for overseas students who are pursuing studies in Shin Buddhism and training to become ministers at temples abroad.